By: Miles, Daniel, Paige, and McKenzie

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By: Daniel, McKenzie Miles, and Paige

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Duchenne Muscular Dystrophy is one of nine types of muscular dystrophy, a group of genetic, degenerative diseases that mostly affects voluntary muscles. The symptoms are Generalized weakness and muscle wasting first affecting the muscles of the hips, pelvic area, thighs and shoulders. Calves are often enlarged. It is caused by an absence of dystrophin, which is a protein that helps keep muscle cells intact.


  1. How does a person inherit it? Is it dominant or recessive? You inherit Duchenne muscular dystrophy when there is a mutation in a DMD gene that you get from mom or dad twice so it is a recessive gene.
  2. What are the possible genotypes of the parents? Duchenne Muscular Dystrophy is a recessive sex-linked disorder. This disease is caused by a mutation in the DMD gene found on the X chromosome. This means that females have two copies of the gene, while males only have one. XM Y: this is a male with a normal DMD gene. He will not develop duchenne muscular dystrophy and will not pass on a mutated gene to any children.Xm Y: this is a male with a mutated DMD gene. He will be affected with duchenne muscular dystrophy. He will pass on that mutated gene to all female children but not male children (Because men get the Y gene). Females who inherit a mutated gene will be carriers of the disease but not be affected themselves.
  3. How prevalent is the disease in the population (include statistics)? Duchenne muscular dystrophy effects 1 in every 3,600 men at birth.
  4. How prevalent is the disease in the population (include statistics)? Worldwide 1 in 3,600 boys have DMD
  5. What are the chances of a person with this disease passing the disease to their offspring (include possible scenarios)? the chances of passing this disease to offspring are there just not forsure. there has ben cases where it has.
  6. How is the disease diagnosed?By clinical features, CPK assay, DNA testing, muscle biopsy, and prenatal testing.
  7. What are the physical symptoms of the disease? The physical symptoms are awkward manner of walking, frequent falls, fatigue, difficulty with motor skills, eventual loss of ability to walk, and skeletal deformities.
  8. What is the life expectancy of someone with the disease? The life expectancy of someone with DMD averages around late teens' to mid-twenties.
  9. How can the disease be treated? It can be treated 099cc40b2d9c81fbb45212a89a4d.jpg Assistive Devices, Genetic Counseling, Medicine, Rehab therapies, and Surgery


  1. What is everyday life like? What is the quality of life? People with DMD have a pretty nice life, but some things they can't really do like bungee jumping, rock climbing, etc.
  2. What limitations does the person have? Some young men will have difficulty with walking, jumping, etc. Some will have to wear leg braces at the age of 12
  3. What are some organizations that can help a family cope with a child's disorder (web links)?
  4. How possible is it that a cure will be found? They say a cure could be possible by excessive gene therapy.


  • Web links to sources of information.
  • Each group member is responsible for writing a literature review of one web site.

Individual pages

Daniel H